Scientific Papers

  • Chanarat, S., Seizl, M., and Sträßer, K. (2011) The Prp19 Complex is a Novel Transcription Elongation Factor Required for TREX Occupancy at Transcribed Genes, Genes Dev., 25: 1147-1158

  • Lammens, K., Bemeleit, D.J., Möckel, C., Clausing, E., Schele, A., Hartung, S., Schiller, C.B., Lucas, M., Angermüller, C., Söding, J., Sträßer, K., and Hopfner, K.-P. (2011) X-ray structure of a bacterial Mre11:Rad50 complex reveals an ATP dependent molecular clamp in DNA double-strand break repair, Cell, 145: 54-66

  • Clausing, E., Mayer, A.*, Chanarat, S.*, Müller, B., Germann, S.M., Cramer, P., Lisby, M., and Sträßer, K. (2010) The transcription elongation factor Bur1-Bur2 interacts with Replication Protein A to maintain genome stability, J. Biol. Chem., 285: 41665-41674 * equal contribution

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  • Röther, S., Burkert, C., Brünger, K.M., Mayer, A., Kieser, A., and Sträßer, K. (2010) Nucleocytoplasmic shuttling of the La motif-containing protein Sro9 might link its nuclear and cytoplasmic functions, RNA, 16: 1393-1401

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  • Röther, S. and Sträßer, K. (2009) mRNA Export – an integrative component of gene expression. In: Nuclear Transport, edited by Ralph Kehlenbach, Austin: Landes Bioscience, review

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  • Jasiak, A.J., Hartmann, H., Karakasili, E., Marian, K., Flatley, A., Kremmer, E., Sträßer, K., Martin, D.E., Söding, J., Cramer, P. (2008) Genome-associated RNA polymerase II includes the dissociable RPB4/7 subcomplex. J. Biol. Chem., 283: 26423-7

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  • Larivière, L., Seizl, M., van Wageningen, S., Roether, S., Feldmann, H., Sträßer, K., Hahn, S., Holstege, F., Cramer, P. (2008) Structure-system correlation identifies a gene regulatory Mediator submodule. Genes Dev. 22: 872-877

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  • Röther, S. and Sträßer, K. (2007) The RNA polymerase II CTD kinase Ctk1 functions in translation elongation. Gen. Dev. 21: 1409-1421

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  • Covered by the perspective “Synchronicity: policing multiple aspects of gene expression by Ctk1” by M. Hampsey and T. G. Kinzy in the same issue of Gen. Dev.

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  • Krebs, S., Medugorac, I., Röther, S., Sträßer, K., and Förster, M. (2007) A missense mutation in the 3-ketodihydrosphingosine reductase FVT1 as candidate causal mutation for bovine spinal muscular atrophy. Proc. Natl. Ac. Sc. USA, 104: 6746-51

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  • Röther, S., Clausing, E., Kieser, A., and Sträßer, K. (2006) Swt1, a novel yeast protein, functions in transcription. J. Biol. Chem. 281: 36518 – 36525

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  • Larivière, L., Geiger, S., Hoeppner, S., Röther, S., Sträßer, K., and Cramer, P. (2006) Structure and TBP binding of the Mediator head subcomplex Med8–Med18–Med20. Nat Struct Mol Biol. 13: 895 – 901

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  • Cramer, P., Sträßer, K., Niessing, D., Meister, G., and Jansen, R.P. (2005) RNA als Koordinator und Regulator der Genexpression. BIOspektrum, Sonderausgabe, 11. Jahrgang, 523-525

  • Hurt, E., Luo, M.J., Röther, S., Reed, R., and Sträßer, K. (2004) Cotranscriptional recruitment of the serine-arginine-rich (SR)-like proteins Gbp2 and Hrb1 to nascent mRNA via the TREX complex. Proc. Natl. Ac. Sc. USA 101: 1858-1862

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  • Fischer, T., Sträßer, K., Rácz, A., Rodriguez-Navarro, S., Oppizzi, M., Ihrig, P., Lechner, J., and Hurt, E. (2002) The mRNA export machinery requires the novel Sac3-Thp1 complex to dock at the nucleoplasmic entrance of the nuclear pores. EMBO J. 21: 5843-5852

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  • Sträßer, K. (2002) Nukleärer mRNA-Export: Wie die messenger RNA vom Genlocus zu den Kernporen gelangt. Biospektrum 5/02: 636/7

  • Sträßer, K. , Masuda, S., Mason, P., Pfannstiel J., Oppizzi M., Rodriguez-Navarro S., Rondón A.G., Aguilera A., Struhl, K., Reed R., and Hurt E. (2002) TREX is a conserved complex coupling transcription with messenger RNA export. Nature 417: 304-308

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  • Rodríguez-Navarro, S., Sträßer, K., and Hurt, E. (2002) An intron in the YRA1 gene is required to control Yra1p protein expression and mRNA export in yeast. EMBO R. 3: 438-442

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  • Katahira, J., Sträßer, K., Saiwaki, T., Yoneda, Y., and Hurt, E. (2002) Complex formation between Tap and p15 affects binding to FG-repeat nucleoporins and nucleocytoplasmic shuttling. J. Biol. Chem. 277: 9242-9246

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  • Sträßer, K. and Hurt, E. (2001) Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p. Nature 413:648-652

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  • Zhou, Z., Luo, M., Sträßer, K., Katahira, J., Hurt, E., and Reed, R. (2000) The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans. Nature 407: 401-405

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  • Sträßer, K., Baßler, J., and Hurt, E. (2000) Binding of the Mex67p/Mtr2p Heterodimer to FXFG-, GLFG-, and FG-Repeat Nucleoporins is essential for Nuclear mRNA Export. J. Cell Biol. 150:695-706

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  • Hurt, E., Sträßer, K., Segref, A., Bailer, S., Schlaich, N., Presutti, C., Tollervey, D., and Jansen, R. (2000) Mex67p mediates nuclear export of a variety of RNA polymerase II transcripts. J. Biol. Chem. 275: 8361-8368

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  • Sträßer, K. and Hurt, E. (2000) Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export. EMBO J. 19: 410-420

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  • Sträßer, K. and Hurt, E. (1999) Nuclear RNA export in yeast (review). FEBS Letters 452: 77-81

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  • Katahira, J., Sträßer, K., Podtelejnikov, A., Mann, M., Jung, J.U., and Hurt, E. (1999) The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human. EMBO J. 18: 2593-2609

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  • Vassella, E., Sträßer, K., and Boshart, M. (1997) A mitochondrion-specific dye for multicolour fluorescent imaging of Trypanosoma brucei. Mol.Biochem.Parasitol. 90: 381-385

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