Scientific Papers

  • Meinel D.M., Burkert-Kautzsch C., Kieser A., O'Duibhir E., Siebert M., Mayer A., Cramer P., Söding J., Holstege FC and Sträßer K. (2013) Recruitment of TREX to the Transcription Machinery by Its Direct Binding to the Phospho-CTD of RNA Polymerase II, PLoS Genet., 9(11):e1003914

  • Burger K., Mühl B., Rohrmoser M., Coordes B., Heidemann M., Kellner M., Gruber-Eber A., Heissmeyer V., Strässer K. and Eick D. (2013) Cyclin-dependent kinase 9 Links RNA polymerase II transcription to processing of ribosomal RNA, JBC, 288(29):21173-21183

  • Chanarat S. and Sträßer K. (2013) Splicing and beyond: the many faces of the Prp19 complex., BBA, 1833(10):2126-21234

  • Miller C., Matic I., Maier K.C., Schwalb B., Roether S., Strässer K., Tresch A., Mann M. and Cramer P. (2012) Mediator phosphorylation prevents stress response transcription during non-stress conditions, JBC, 287(53):44017-44026

  • Schiller C.B., Lammens K., Guerini I., Coordes B., Feldmann H., Schlauderer F., Möckel C., Schele A., Sträßer K., Jackson S.P., and Hopfner K.P. (2012) Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling, NSMB, 19,693–700

  • Chanarat S., Burkert-Kautzsch C., Meinel D.M., and Sträßer K. (2012) Prp19C and TREX: interacting to promote transcription elongation
and mRNA export, Transcription,3(1): 8-12.

  • Schenk L., Meinel D.M., Sträßer K., and Gerber A.P. (2012) La-motif-dependent mRNA association with Slf1 promotes copper detoxification in yeast, RNA, 18(3):449-61

  • Chanarat, S., Seizl, M., and Sträßer, K. (2011) The Prp19 Complex is a Novel Transcription Elongation Factor Required for TREX Occupancy at Transcribed Genes, Genes Dev., 25: 1147-1158

  • Lammens, K., Bemeleit, D.J., Möckel, C., Clausing, E., Schele, A., Hartung, S., Schiller, C.B., Lucas, M., Angermüller, C., Söding, J., Sträßer, K., and Hopfner, K.-P. (2011) X-ray structure of a bacterial Mre11:Rad50 complex reveals an ATP dependent molecular clamp in DNA double-strand break repair, Cell, 145: 54-66

  • Clausing, E., Mayer, A.*, Chanarat, S.*, Müller, B., Germann, S.M., Cramer, P., Lisby, M., and Sträßer, K. (2010) The transcription elongation factor Bur1-Bur2 interacts with Replication Protein A to maintain genome stability, J. Biol. Chem., 285: 41665-41674 * equal contribution

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  • Röther, S., Burkert, C., Brünger, K.M., Mayer, A., Kieser, A., and Sträßer, K. (2010) Nucleocytoplasmic shuttling of the La motif-containing protein Sro9 might link its nuclear and cytoplasmic functions, RNA, 16: 1393-1401

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  • Röther, S. and Sträßer, K. (2009) mRNA Export – an integrative component of gene expression. In: Nuclear Transport, edited by Ralph Kehlenbach, Austin: Landes Bioscience, review

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  • Jasiak, A.J., Hartmann, H., Karakasili, E., Marian, K., Flatley, A., Kremmer, E., Sträßer, K., Martin, D.E., Söding, J., Cramer, P. (2008) Genome-associated RNA polymerase II includes the dissociable RPB4/7 subcomplex. J. Biol. Chem., 283: 26423-7

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  • Larivière, L., Seizl, M., van Wageningen, S., Roether, S., Feldmann, H., Sträßer, K., Hahn, S., Holstege, F., Cramer, P. (2008) Structure-system correlation identifies a gene regulatory Mediator submodule. Genes Dev. 22: 872-877

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  • Röther, S. and Sträßer, K. (2007) The RNA polymerase II CTD kinase Ctk1 functions in translation elongation. Gen. Dev. 21: 1409-1421

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  • Covered by the perspective “Synchronicity: policing multiple aspects of gene expression by Ctk1” by M. Hampsey and T. G. Kinzy in the same issue of Gen. Dev.

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  • Krebs, S., Medugorac, I., Röther, S., Sträßer, K., and Förster, M. (2007) A missense mutation in the 3-ketodihydrosphingosine reductase FVT1 as candidate causal mutation for bovine spinal muscular atrophy. Proc. Natl. Ac. Sc. USA, 104: 6746-51

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  • Röther, S., Clausing, E., Kieser, A., and Sträßer, K. (2006) Swt1, a novel yeast protein, functions in transcription. J. Biol. Chem. 281: 36518 – 36525

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  • Larivière, L., Geiger, S., Hoeppner, S., Röther, S., Sträßer, K., and Cramer, P. (2006) Structure and TBP binding of the Mediator head subcomplex Med8–Med18–Med20. Nat Struct Mol Biol. 13: 895 – 901

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  • Cramer, P., Sträßer, K., Niessing, D., Meister, G., and Jansen, R.P. (2005) RNA als Koordinator und Regulator der Genexpression. BIOspektrum, Sonderausgabe, 11. Jahrgang, 523-525

  • Hurt, E., Luo, M.J., Röther, S., Reed, R., and Sträßer, K. (2004) Cotranscriptional recruitment of the serine-arginine-rich (SR)-like proteins Gbp2 and Hrb1 to nascent mRNA via the TREX complex. Proc. Natl. Ac. Sc. USA 101: 1858-1862

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  • Fischer, T., Sträßer, K., Rácz, A., Rodriguez-Navarro, S., Oppizzi, M., Ihrig, P., Lechner, J., and Hurt, E. (2002) The mRNA export machinery requires the novel Sac3-Thp1 complex to dock at the nucleoplasmic entrance of the nuclear pores. EMBO J. 21: 5843-5852

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  • Sträßer, K. (2002) Nukleärer mRNA-Export: Wie die messenger RNA vom Genlocus zu den Kernporen gelangt. Biospektrum 5/02: 636/7

  • Sträßer, K. , Masuda, S., Mason, P., Pfannstiel J., Oppizzi M., Rodriguez-Navarro S., Rondón A.G., Aguilera A., Struhl, K., Reed R., and Hurt E. (2002) TREX is a conserved complex coupling transcription with messenger RNA export. Nature 417: 304-308

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  • Rodríguez-Navarro, S., Sträßer, K., and Hurt, E. (2002) An intron in the YRA1 gene is required to control Yra1p protein expression and mRNA export in yeast. EMBO R. 3: 438-442

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  • Katahira, J., Sträßer, K., Saiwaki, T., Yoneda, Y., and Hurt, E. (2002) Complex formation between Tap and p15 affects binding to FG-repeat nucleoporins and nucleocytoplasmic shuttling. J. Biol. Chem. 277: 9242-9246

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  • Sträßer, K. and Hurt, E. (2001) Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p. Nature 413:648-652

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  • Zhou, Z., Luo, M., Sträßer, K., Katahira, J., Hurt, E., and Reed, R. (2000) The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans. Nature 407: 401-405

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  • Sträßer, K., Baßler, J., and Hurt, E. (2000) Binding of the Mex67p/Mtr2p Heterodimer to FXFG-, GLFG-, and FG-Repeat Nucleoporins is essential for Nuclear mRNA Export. J. Cell Biol. 150:695-706

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  • Hurt, E., Sträßer, K., Segref, A., Bailer, S., Schlaich, N., Presutti, C., Tollervey, D., and Jansen, R. (2000) Mex67p mediates nuclear export of a variety of RNA polymerase II transcripts. J. Biol. Chem. 275: 8361-8368

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  • Sträßer, K. and Hurt, E. (2000) Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export. EMBO J. 19: 410-420

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  • Sträßer, K. and Hurt, E. (1999) Nuclear RNA export in yeast (review). FEBS Letters 452: 77-81

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  • Katahira, J., Sträßer, K., Podtelejnikov, A., Mann, M., Jung, J.U., and Hurt, E. (1999) The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human. EMBO J. 18: 2593-2609

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  • Vassella, E., Sträßer, K., and Boshart, M. (1997) A mitochondrion-specific dye for multicolour fluorescent imaging of Trypanosoma brucei. Mol.Biochem.Parasitol. 90: 381-385

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